Endocrine Abstracts

Introduction: Polycystic ovary syndrome (PCOS) is a frequent metabolic disorder in women of the reproductive age, and is characterized by multi-factorial cardiovascular risk factors. Insulin resistance is proposed as a central factor linking PCOS to increasing risk of cardiovascular disease. The aim of our study was to explore a link between insulin resistance and oxidative stress, as a predictor of cardiovascular risk, in young, non-obese PCOS women.Met...

It is supposed a simillar dirnal change of TSH, free fatty acids (FFA) and leptin in humans. Hypothalamic-pituitary-thyroid axis (HPT) is suppressed during food deprivation while there is an elevation of FFA further influencing glucose metabolism. The aim of our study was to investigate whether leptin can act as a metabolic signal linking the adipose tissue metabolism and the HPT. We studied 13 women with polycystic ovary disease-PCOS (mean age: 26.6±1.83 years; BMI: 34...